What’s in those IV bags almost every hospital patient gets and is it dangerous?


Saline solution IV bags are one of the most common items in hospitals. But new research suggests replacing the saline with a different intravenous solution may significantly reduce the risk of death and kidney damage in patients.

>> Read more trending news 

According to the study, which was discussed at a critical care conference in San Antonio and published by the New England Journal of Medicine, switching from saline could save between 50,000 and 70,000 lives in the United States every year. Ditching the common solution could also reduce cases of kidney failure by 100,000.

"We found that these balanced solutions tended to make people live longer and have less kidney damage," Dr. Wesley Self, a physician and researcher at Vanderbilt University Medical Center, who was involved in the research, told News Channel 5.

Vanderbilt has already made the decision to drop saline solution, replacing it with a balanced solution instead. The university decided to make the shift based on the new research, which found that saline has a higher concentration of sodium and chloride than blood does. On the other hand, the balanced solution is much closer to normal blood levels of sodium and chloride.

During a two-year period, Vanderbilt researchers carried out two studies involving 28,000 patients. The data collected showed that negative outcomes, such as death or kidney failure, were about one percent less likely with the balanced solution. Although the percentage may seem small, when it comes to something so common as an IV, large numbers of patients are affected.

>> Related: Dad who wore T-shirt asking for a kidney to Walt Disney World receives transplant

"When you look at the millions and millions of patients that have fluids given to them every year in the U.S., a one percent difference for each patient starts to be a big number when you multiply it out by millions," Self said.

Critical care specialists have welcomed the research, saying they have long been concerned about the potential problems of saline.

"We've been sounding the alarm for 20 years" about possible harms from saline, Dr. John Kellum, a critical care specialist at the University of Pittsburgh, who wasn't involved with the research, told CBS News. "It's purely inertia" that prevents a change, he added.

The balanced fluids now being used by Vanderbilt cost approximately the same as saline, a dollar or two per IV, meaning switching shouldn't cause any long-term financial issues for hospitals and other medical facilities, according to The Chicago Tribune.

>> Related: What is the DASH diet? Heart-healthy diet may also reduce risk of depression

There has been a shortage of IV bags due to Hurricane Maria, which hit Puerto Rico hard last fall. Baxter International, one of the biggest makers of the saline fluids, had electricity cut to three of its plants on the island, temporarily halting production

"It's just really nerve-racking to think about not being able to have those bags available to the patient," Régine Villain, who manages supplies at New York University Langone Health, said about a month after the hurricane hit.

Villain also pointed out that hooking patients up to an IV is one of the most routine things health professionals do.

"[It's] the first thing we do – we use an IV, we hang an IV and that's how we start taking care of you," she said.

However, according to the new research, this simple routine action may currently be putting thousands at serious risk.

>> Related: Florida teacher donates kidney to student’s mother

"There are tens or hundreds of thousands of patients who would be spared death or severe kidney problems by using balanced fluids instead of saline," Dr. Matthew Semler, one of the study's leaders, said.


Reader Comments ...


Next Up in Nation & World

Toys R Us announces day stores will close for good
Toys R Us announces day stores will close for good

Toys R Us will be no more after next week. The toy retailer, which started liquidating in March, has said that all Toys R Us and Babies R Us locations will close on or before next Friday, June 29 via posts on the company’s social media pages. The locations that are still open are currently offering what’s left for up to 70 percent off....
Who was XXXTentacion? 5 things about the late rapper
Who was XXXTentacion? 5 things about the late rapper

Hip-hop fans and celebrities are mourning the loss of rapper XXXTentacion after news of his death broke early this week. On Monday, the rapper, 20, was shot and killed while sitting in his car in Deerfield Beach, Florida. Broward Sheriff’s Office spokeswoman Gina Carter confirmed Thursday that Dedrick Williams, 22, was arrested in connection...
Paul McCartney, James Corden visit Beatles landmarks in Liverpool for Carpool Karaoke
Paul McCartney, James Corden visit Beatles landmarks in Liverpool for Carpool Karaoke

Sir Paul McCartney has had a legendary run, from The Beatles to Wings and then a solo career  that has gone on for decades, but nothing can compare with his latest performance -- Carpool Karaoke with James Corden. McCartney gave the host of “The Late Late Show” a little “Help” as they drove down “Penny...
Study: Republicans see ‘misinformation’ in media at twice the rate of Democrats
Study: Republicans see ‘misinformation’ in media at twice the rate of Democrats

Fresh data affirm a long-running crisis for U.S. media organizations: Republicans and conservatives just don't trust them. A May 2017 Pew Research Center noted in stark terms how the media-trust gap is widening between the parties. Now comes a Gallup/Knight Foundation survey with a finding that cements common wisdom on the topic.  Asked to estimate...
Tabloid allegedly ran stories by Trump before publishing
Tabloid allegedly ran stories by Trump before publishing

During the presidential campaign, National Enquirer executives sent digital copies of the tabloid's articles and cover images related to Donald Trump and his political opponents to Trump's attorney Michael Cohen in advance of publication, according to three people with knowledge of the matter — an unusual practice that speaks to the close relationship...
More Stories